The prime medicinal use of spicebush has been as a febrifuge, or agent that reduces fever. Folk healers still use the shrub for this purpose and they also recommend it for colds and as a tonic. There is very little scientific data available to validate these claims. Since colonial times, the berries have served cooks as a substitute for allspice. The leaves make a refreshing tea, and in spring the blossoms can be added for extra sweetness.